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Allele : Mirc34<tm1.2Mrl> microRNA cluster 34, including Mir449a through Mir449c; targeted mutation 1.2, Merck Research Laboratory
Primary Identifier  MGI:6436279 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mirc34
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  The cluster containing Mir449a, Mir449b and Mir449c was flanked by loxP sites. The cluster Mir449 is embedded into intron 2 of the predicted mouse gene Cdc20b (ENSMUSG00000078926). Mir449c is located 206 bp downstream of the predicted exon 2 of the Cdc20b gene. The proximal LoxP site was inserted within these 206 bp. Recombination removed the selection cassette and microRNA cluster.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Mutation Involves

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Mouse alleles --> Mammalian phenotypes (MP terms)

 

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