Primary Identifier | MGI:6441961 | Allele Type | Endonuclease-mediated |
Attribute String | Modified regulatory region | Gene | Tbx6 |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated a 47 bp deletion in the 5' regulatory region (chr7:126781201-126781247, GRCm38/mm10) of Tbx6. qRT-PCR and RNA in situ hybridization indicate that Tbx6 RNA expression is elevated. |