| Primary Identifier | MGI:6436699 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Gcn1 |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology was used to induce double-strand breaks within introns 1 and 2 and excise exon 2, resulting in a frameshift and premature stop codon in exon 3. Homozygous mutant mice only express a short form of the protein, consisting of the N-terminus 12 amino acids and lacking the eEF3-like domain and RWD binding domain. |
