Primary Identifier | MGI:6456553 | Allele Type | Transgenic |
Attribute String | Epitope tag, Inserted expressed sequence | Gene | Tg(Myh6-Sgk1*S436D)1Anr |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgenic construct contains a hemagluttinin (HA) tagged mutant mouse Sgk1 sequence under the control of the cardiac-specific Myh6 promoter. The CA mutation replaces a serine at residue 436 (published as 422) for an aspartic acid (S436D), rendering the kinase constitutively active (CA). |