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Allele : Spg11<tm1.1Ics> SPG11, spatacsin vesicle trafficking associated; targeted mutation 1.1, Mouse Clinical Institute
Primary Identifier  MGI:6451766 Allele Type  Targeted
Attribute String  Null/knockout Gene  Spg11
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Two successive stop codons were inserted in exon 32 of the gene. The mutations introduced were c.6052C > T (p.Arg2018*), corresponding to c.6091C > T (p.Arg2031*) in human and c.6061C > T (p.Gln2021*), corresponding to c.6100C > T (p.Arg2034*) in human. An adjacent frt-flanked neomycin resistance cassette was removed via FLP-mediated recombination.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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