| Primary Identifier | MGI:6460395 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Dguok |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 2. An FRT-flanked PGK-neomycin selection cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination simultaneously removed exon 2 and the selection cassette. Real-time PCR analysis confirmed the absence of mRNA expression in liver tissue from homozygous mutant mice. |