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Allele : Tet1<tm1.1Koh> tet methylcytosine dioxygenase 1; targeted mutation 1.1, Kian Peng Koh

Primary Identifier  MGI:6467253 Allele Type  Targeted
Attribute String  Reporter Gene  Tet1
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A target vector was designed to insert an loxP-NLS-lacZ-loxP-mCherry-FRT-neo-FRT cassette (containing ATG start codon and nuclear localization signal sequence 5 of lacZ reporter gene with 3 BGH polyA, flanked by 2 LoxP sites to allow reporter exchange to a downstream ATG-mCherry-pA cassette by Cre recombination, followed by a FRT-flanked neomycin selection cassette) in-frame at the ATG start codon in exon 2. Flp-mediated recombination removed the selection cassette.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele