| Primary Identifier | MGI:6460464 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Adtrp |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted into intron 1, a second loxP site and an FRT site flanked neomycin resistance gene cassette into intron 2, a third loxP site into intron 4, and a fourth loxP site and an FRT site flanked hygromycin resistance gene cassette into intron 5. Subsequent ROSA26-Flpe-mediated deletion of the neo and hygro cassettes also deleted exons 3-5 in some mice, creating this knockout allele. Very low expression levels from this allele were confirmed by qPCR. |
