Primary Identifier | MGI:6467827 | Allele Type | Targeted |
Attribute String | Inducible, Recombinase, Reporter | Gene | Smoc2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | An EGFP-IRES-creERT2 cassette was inserted at the translational start site of the gene along with a loxP-flanked neomycin cassette. The neomycin gene was then excised in vivo by crossing with a cre-deleter strain. EGFP expression is driven by the endogenous promoter. Cre expression is induced in Smoc2 expressing cells by tamoxifen treatment. |