| Primary Identifier | MGI:6469949 | Allele Type | Targeted |
| Attribute String | Conditional ready, Humanized sequence, Null/knockout | Gene | Kras |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site flanked STOP cassette, with a 5' puromycin resistance gene cassette, was inserted into intron 2. Endogenous exon 3 was modified to harbor a C-to-T mutation at codon 58, resulting in a threonine to isoleucine mutation (p.T58I) associated with patients with Noonan syndrome (NS). |
