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Allele : Pycr2<tm1.1Brre> pyrroline-5-carboxylate reductase family, member 2; targeted mutation 1.1, Bruno Reversade

Primary Identifier  MGI:6470408 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pycr2
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 3-6 were replaced with a loxP site flanked neomycin resistance gene cassette. The neo cassette was removed through subsequent cre-mediated recombination. Western blot and immunofluorescence studies of primary dermal fibroblasts confirmed the lack of protein expression from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele