Primary Identifier | MGI:6469530 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence, Reporter | Gene | Tg(Prnp-Tardbp,-EGFP)19Zxu |
Strain of Origin | FVB/NJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A loxP site, mouse Tardbp DNA binding protein cDNA sequence, an internal ribosome entry site (IRES), an enhanced green fluorescent protein sequence (EGFP), a second loxP site and polyA sequence was inserted between exon 2 and exon 3 of mouse Prnp gene. Founder line 19 was identified with GFP expression in central nervous system and desirable Tardbp expression level/pattern. |