| Primary Identifier | MGI:6471912 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Mafb |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology generated a T to C point mutation at position 716 (c.716T>C) resulting in a leucine to proline change at amino acid 239 (p.Leu239Pro) using gRNA 5'-TCCGCCGCTTCTGCTTCAGG-3'. Focal segmental glomerulosclerosis affected individuals harbor this rare heterozygous substitution. |
