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Allele : Obscn<MSN/GammMmmh> obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF; MSN/GammMmmh

Primary Identifier  MGI:6471803 Allele Type  Spontaneous
Gene  Obscn Strain of Origin  MSN/GammMmmh
Is Recombinase  false Is Wild Type  false
molecularNote  This allele contains the following spontaneous mutation(s) that have a predicted consequential effect on the encoded peptide and that are specific to (fixed in) the MSN (Madison) strain used as a mania model, as compared to: the Hsd:ICR strain from which it is derived; the MaD2 (Maternal Defense 2) strain, which is also derived from Hsd:ICR but wasn't selected for mania; the C57BL/6J reference strain. Build GRCm38 genomic coordinates: g.chr11:59000521C>CTGG (p.P7061dup); g.chr11:59000884C>T (p.V6941M); g.chr11:59076137G>A (p.H3164Y).
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Obscn<V1583PV V6941M H586Y>,
  • Obscn<V1583PV V6941M H586Y>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele