Primary Identifier | MGI:6471804 | Allele Type | Spontaneous |
Gene | Trpv1 | Strain of Origin | MSN/GammMmmh |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This allele contains the following spontaneous mutation(s) that have a predicted consequential effect on the encoded peptide and that are specific to (fixed in) the MSN (Madison) strain used as a mania model, as compared to: the Hsd:ICR strain from which it is derived; the MaD2 (Maternal Defense 2) strain, which is also derived from Hsd:ICR but wasn't selected for mania; the C57BL/6J reference strain. Build GRCm38 genomic coordinates: g.chr11:73240601C>G (p.P322A); g.chr11:73254291C>A (p.D734E). |