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Allele : Trp53<tm2Thst> transformation related protein 53; targeted mutation 2, Thorsten Stiewe

Primary Identifier  MGI:6479073 Allele Type  Targeted
Attribute String  Null/knockout Gene  Trp53
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 5 was replaced with a modified one in which nucleotide substitutions CGC-to-GAG result in the amino acid substitution of arginine with glutamic acid at position 178 (p.R178E). A loxP site flanked STOP cassette was inserted into intron 1.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Trp53<LSL-R178E>,
  • p53LSL-EE,
  • p53LSL-R178E,
  • p53LSL-R178E,
  • p53LSL-EE,
  • Trp53<LSL-R178E>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele