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Allele : Trp53<tm2.1Thst> transformation related protein 53; targeted mutation 2.1, Thorsten Stiewe
Primary Identifier  MGI:6479078 Allele Type  Targeted
Attribute String  Not Specified Gene  Trp53
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 5 was replaced with a modified one in which nucleotide substitutions (CGC-to-GAG) result in the amino acid substitution of arginine with glutamic acid at position 178 (p.R178E). Cre-mediated recombination removed a loxP site flanked STOP cassette that was inserted into intron 1.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Trp53<R178E>,
  • Trp53<R178E>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele




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