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Allele : Gt(ROSA)26Sor<tm6(RET*,tdTomato)Cos> gene trap ROSA 26, Philippe Soriano; targeted mutation 6, Franklin Costantini
Primary Identifier  MGI:6501786 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (C57BL/6J x 129S6/SvEvTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector was designed with, from 5' to 3', a floxed-STOP cassette that contains a neomycin cassette, a constitutively active mutant form of the mouse ret proto-oncogene cDNA, a viral T2A sequence, and a human histone H2B fused to a constitutively active red enhanced green fluorescence protein (tdTomato). The mutation in Ret is found in patients with multiple endocrine neoplasia type 2A.
  • mutations:
  • Insertion
  • synonyms:
  • Rosa26-RetMEN2A-H2BTom,
  • Rosa26-RetMEN2A-H2BTom
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

3 Publication categories

Trail: Allele




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