Primary Identifier | MGI:6505588 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | C4b |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Using sgRNAs and ssODN templates with CRISPR/Cas9 technology, the gene was changed to make the isotypic region resemble the human C4A gene: endogenous codon sequence for PCPVIH was changed to PCPVLD (p.I1120_H1121delLDins) |