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Allele : St18<tm1c(KOMP)Wtsi> suppression of tumorigenicity 18; targeted mutation 1c, Wellcome Trust Sanger Institute

Primary Identifier  MGI:6489608 Allele Type  Targeted
Attribute String  Conditional ready Gene  St18
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
molecularNote  The L1L2_Bact_P cassette was inserted at position 6808853 of Chromosome 1 into intron9 (Build GRCm38). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted into intron 10 at position 6809630. Exon 10 is thus flanked by loxP sites. A "conditional ready" (floxed) allele was created through flp-mediated removal of the LacZ and neo cassettes.
  • mutations:
  • Insertion
  • synonyms:
  • St18<fl>,
  • St18<fl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele