| Primary Identifier | MGI:6490502 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Ppp3r1 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An A to C change at position 305 resulting in an aspartate to alanine substitution at amino acid 102 (p.D102A) was introduced into exon 4. In addition, a loxP-flanked neomycin selection cassette was inserted between exon 3 and 4, which was removed via cre-mediated recombination. The p.D102A variant was detected in a proband with dilated cardiomyopathy. |
