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Allele : Ace2<em1Pbmj> angiotensin converting enzyme 2; endonuclease-mediated mutation 1, Paul McCray

Primary Identifier  MGI:6491923 Allele Type  Endonuclease-mediated
Gene  Ace2 Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/cas9 endonuclease-mediated genome editing is used to create an amino acid substitution at position 353 (histidine to lysine, H353K, CAC to AAA) in exon 8 (isoform Ace2-201). The mutation was confirmed by sequencing.
  • mutations:
  • Insertion
  • synonyms:
  • Ace2<H353K>,
  • Ace2<H353K>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele