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Allele : Tg(Spp1-icre/ERT2)#Lecl transgene insertion, Isabelle A Leclercq
Primary Identifier  MGI:6514326 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(Spp1-icre/ERT2)#Lecl
Strain of Origin  Not Specified Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  The mouse was generated via bacterial artificial chromosome transgenesis using the 187kb BAC clone (RP24-327i14) containing the murine Spp1 and Pkd2 genes. Two successive recombinations were performed to insert iCreERT24 in the Spp1 gene and to inactivate the Pkd2 gene. An iCreERT2-polyA-FRTAmpR-FRT fragment was used to insert iCreERT2 in frame and downstream of the initiator ATG of the Spp1 gene. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled.
  • mutations:
  • Insertion
  • synonyms:
  • OPN-iCre- ER<T2>,
  • OPN-iCre- ER<T2>
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1 Feature

Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

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Trail: Allele




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