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Allele : Lgr5<tm2.1(Hbegf)Niba> leucine rich repeat containing G protein coupled receptor 5; targeted mutation 2.1, Nick Barker
Primary Identifier  MGI:6507039 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Lgr5
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence for the self-cleaving A2 peptide, a diphtheria toxin receptor (HBEGF/DTR) cDNA and a loxP site flanked neomycin resistance gene cassette were inserted immediately upstream of the endogenous stop codon. The neo cassette was removed through subsequent cre-mediated recombination. This allele expresses the endogenous peptide and the inserted DTR peptide.
  • mutations:
  • Insertion
  • synonyms:
  • Lgr5-2A-DTR,
  • Lgr5-2A-DTR
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

7 Publication categories

Trail: Allele




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