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Allele : Lbhd2<em1(cre/ERT2)Fuki> LBH domain containing 2; endonuclease-mediated mutation 1, Izumi Fukunaga
Primary Identifier  MGI:6508398 Allele Type  Endonuclease-mediated
Attribute String  Inducible, Recombinase Gene  Lbhd2
Transmission  Germline Strain of Origin  C57BL/6JJcl
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  Using CRISPR/cas9 technology an IRES enhancer sequence, a CreER(T2) fusion gene, and a rabbit globin polyadenylation (rGpA) termination sequence were inserted immediately downstream of the LBH domain containing 2 locus of the Lbhd2 gene on chromosome 12. The construct was electroporated into C57BL/6JJcl-derived embryonic stem (ES) cells. Correctly targeted ES cells were injected into recipient blastocysts, and chimeric mice were bred with C57BL/6JJcl for germline transmission.
  • mutations:
  • Insertion
  • synonyms:
  • Lbhd2-IRES-CreERT2,
  • Lbhd2-IRES-CreERT2
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0 Mutation Involves

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