| Primary Identifier | MGI:6508377 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Tril |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | LoxP sites and an frt-flanked neomycin selection cassette were inserted to flank the coding exon. The coding exon and neomycin selection cassette were deleted via Cre-mediated recombination in the germline. RT-PCR analysis of brain lysates confirmed the absence of mRNA expression in the brain of homozygous mutant mice while moderate to high expression was observed in heterozygous and wild-type mice, respectively. |
