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Allele : Nlrc4<em1Vnce> NLR family, CARD domain containing 4; endonuclease-mediated mutation 1, Russell Vance

Primary Identifier  MGI:6508701 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Nlrc4
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  A 1 bp insertion (or duplication of a T) was created using an sgRNA (targeting CTCTGGAGGCAGGAATCAAT) with CRISPR/Cas9 technology. The resulting frameshift leads to a premature stop codon. Western blot experiments confirmed the lack of peptide expression from this allele.
  • mutations:
  • Insertion
  • synonyms:
  • Nlrc4<->,
  • Nlrc4<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele