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Allele : Cfap45<em1Hmd> cilia and flagella associated protein 45; endonuclease-mediated mutation 1, Hiroshi Hamada

Primary Identifier  MGI:6509073 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Cfap45
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 mediated genome editing technology was used to delete exon 3. Immunofluorescence microscopy analysis confirmed the absence of protein in respiratory cilia of the trachea, multiciliated epithelia of the Fallopian tube, and multiciliated ependyma of the brain in homozygous mutant mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Cfap45<->,
  • Cfap45<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele