| Primary Identifier | MGI:6509042 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Dsc2 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted into intron 1 and an FRT site flanked neomycin selection cassette and a second loxP site into intron 2. The neo cassette was removed via flp-mediated recombination and exon 2 was deleted via cre-mediated recombination in the germline. Western blot and qRT-PCR experiments confirmed the lack of peptide and transcript expression from this allele in liver and heart. |
