| Primary Identifier | MGI:6715678 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Tmc1 |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/cas9 genome editing is used to introduce a T416K (AAC to AAG) mutation to exon 12 to modify residues near the putative channel pore. A silent mutation was also added to create a Dde1 restriction enzyme site. The mutation is homologous to the pathogenic human T422K mutation. |
