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Allele : Cnot8<tm1.2Tya> CCR4-NOT transcription complex, subunit 8; targeted mutation 1.2, Tadashi Yamamoto

Primary Identifier	MGI:6695887	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Cnot8
Transmission	Germline	Strain of Origin	(C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase	false	Is Wild Type	false

molecularNote

A conditional allele was generated by flanking exon 3 with loxP sites. Flp-mediated recombination removed the selection cassette inserted upstream of exon 3. Cre-mediated recombination removed the floxed exon.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Mostafa D, et al. (2020) Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability. RNA Biol 17(3):403-416

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

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