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Allele : Tg(CAG-ACE2)GT5-027Cyt transgene insertion GT5-027, Ching-Yen Tsai
Primary Identifier  MGI:6711183 Allele Type  Transgenic
Attribute String  Epitope tag, Humanized sequence, Inserted expressed sequence Gene  Tg(CAG-ACE2)GT5-027Cyt
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  The transgenic construct contains 2 copies of a chicken HS4 insulator sequence, a CMV enhancer/chicken beta-actin (CAG) promoter, full length a hemaglutatin (HA) tagged human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (hACE2) cDNA, and 2 more copies of the chicken HS4 insulator. Founder lines GT5-027 and GT4-008 were generated. GT5-027 carries two copies of the transgene and was used in experiments. High expression levels are detected in lung, kidney and brain.
  • mutations:
  • Insertion
  • synonyms:
  • CAG-hACE2,
  • CAG-hACE2
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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