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Allele : Slc48a1<em1Ih> solute carrier family 48 (heme transporter), member 1; endonuclease-mediated mutation 1, Iqbal Hamza

Primary Identifier  MGI:6711492 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Slc48a1
Strain of Origin  (C57BL/6J x 129)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/cas9 mediated recombination created a 2 bp deletion in exon 1 resulting in a frameshift mutation in the region after the first transmembrane domain. While mRNA was detected immunoblot and immunohistochemical analysis confirmed the absence of protein in reticuloendothelial tissues from homozygous mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • M6,
  • M6
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele