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Allele : Tc(HSA17)2Mdk transchromosomal, human 17, line 2, Michael Koob; transchromosomal, human 17, line 2, Michael D Koob
Primary Identifier  MGI:6705045 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tc(HSA17)2Mdk
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  A 157 kb deletion on mouse chromosome 11 stretching from, but not including, Crhr1 to Kansl1 is replaced by a syntenic 190 kb region from human chromosome 17 (HSA17). The mouse Sppl2c (signal peptide peptidase 2C) and Mapt (microtubule-associated protein tau) genes are replaced by human SPPL2C and MAPT (H1 haplotype) genes. A loxN-flanked neomycin resistance cassette was removed by transient cre expression.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • MAPT(H1.0)-GR,
  • MAPT(H1.0)-GR
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1 Feature

Trail: Allele

Genome

4 Expresses

Trail: Allele

6 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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3 Carried By

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0 Driven By

4 Publication categories

Trail: Allele




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