| Primary Identifier | MGI:6696146 | Allele Type | Endonuclease-mediated |
| Attribute String | Hypomorph | Gene | Snrnp40 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR-targeting was used to produce a C-to-G mutation in the splice acceptor region of intron 4 (changing it from CAG to GAG) to exclude exon 5 in the mature transcript. Additionally, the allele contains a synonymous exonic nucleotide substitution 11 bp 3' to the primary mutation site. The splice region mutation recreates the spontaneous mutation found in C57BL/6J mice: Snrnp40 |
