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Allele : Foxp3<tm11.1Ayr> forkhead box P3; targeted mutation 11.1, Alexander Y Rudensky

Primary Identifier  MGI:6711581 Allele Type  Targeted
Attribute String  Conditional ready, Modified regulatory region, No functional change, Reporter Gene  Foxp3
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A GFP reporter gene was inserted within the 5’ untranslated region. The upstream conserved non-coding sequence 0 (CNS0 (Rr122); a STAT5-binding enhancer located at chrX:7,570,674–7,571,274 (GRCm38) within intron 1 of Ppp1r3f) was flanked upstream by a loxP site and downstream by an FRT site flanked neomycin resistance gene cassette and a second loxP site. Flp-mediated recombination removed the neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • CNS0<FL>,
  • CNS0<FL>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele