| Primary Identifier | MGI:6711582 | Allele Type | Targeted |
| Attribute String | Modified regulatory region | Gene | Foxp3 |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A GFP reporter gene was inserted in-frame with the 5' end of the gene's coding sequence. The upstream conserved non-coding sequence 0 (CNS0 (Rr122), a STAT5-binding enhancer located at chrX:7436913-7437513 (GRCm39) within intron 1 of Ppp1r3f) was flanked upstream by a loxP site and downstream by an FRT site flanked neomycin resistance gene cassette and a second loxP site. Flp-mediated recombination removed the neo cassette. Cre-mediated recombination removed CNS0. |
