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Allele : Atm<tm1.1Mfgc> ataxia telangiectasia mutated; targeted mutation 1.1, Mammalian Functional Genomics Centre
Primary Identifier  MGI:6714059 Allele Type  Targeted
Attribute String  Not Specified Gene  Atm
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Glutamine codon 35 (CAG) in exon 2 was changed to a stop codon (TAG) (c.103C>T:p.Q35*). A loxP site flanked cassette, consisting of the human ACTB promoter, inactivated TK1 gene, sequence coding for T2A-self-cleaving peptide and neomycin resistance gene cassette, in intron 2 was excised by Cre-mediated recombination.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Atm<Q35X>,
  • Atm<TM1.1(103C)T)Mfgc>,
  • Atm<TM1.1(103C)T)Mfgc>,
  • Atm<Q35X>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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4 Publication categories

Trail: Allele




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