Primary Identifier | MGI:6715274 | Allele Type | Endonuclease-mediated |
Attribute String | Not Specified | Gene | Odaph |
Strain of Origin | C57BL/6N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR-targeting generated a stop codon at 41 cysteine (TGC) to Stop (TGA), which was predicted to result in loss of function. This codon change corresponded to the ODAPH (c.129C>A [p.Cys43*]) mutation identified in an Iraqi family with amelogenesis imperfecta, AI2A4 |