| Primary Identifier | MGI:6718303 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Trp53 |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A G to C mutation resulting in an arginine to histidine substitution at amino acid 334 (R334H) was introduced in exon 10 and a loxP-flanked cassette containing neomycin resistance and thymidine kinase genes was inserted in intron 9. This is a mutation associated with variable tumor susceptibility in humans. |
