| Primary Identifier | MGI:6718974 | Allele Type | Targeted |
| Attribute String | Conditional ready | Gene | Meis2 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting vector introduced loxP sites flanking mouse Meis2 exon 3 and FRT-PGK-gb2-neo-FRT cassette. The targeting vector was electroporated into ES cells. Chimeras were generated by ES cell aggregation. The neomycin resistance cassette was eliminated by crossing with a Flpe deleted mouse. Deletion of this exon results in a premature stop codon, which eliminates all functional domains of the Meis2 protein. |
