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Allele : Cdkn2a<tm1(cre/ERT2)Mkt> cyclin dependent kinase inhibitor 2A; targeted mutation 1, Makoto Nakanishi

Primary Identifier  MGI:6726124 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Cdkn2a
Transmission  Germline Strain of Origin  C57BL/6
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  The exon 1 alpha of the Cdkn2a gene was replaced with a translation start site, a CreERT2 expression cassette and a neo cassette. The retained neo-resistant gene markedly resulted in higher labeling efficacy at this locus presumably due to the fact that a retained neo-resistant cassette can act as a local enhancer to augment reporter expression without compromising tissue reporter fidelity.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • p16<Ink4a>-Cre<ERT2>neo,
  • p16<Ink4a>-Cre<ERT2>neo,
  • p16-Cre<ERT2>,
  • p16-Cre<ERT2>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

3 Publication categories

Trail: Allele