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Allele : Pdgfrb<tm1.2(flpo)Leol> platelet derived growth factor receptor, beta polypeptide; targeted mutation 1.2, Lorin E Olson
Primary Identifier  MGI:6731087 Allele Type  Targeted
Attribute String  Null/knockout, Recombinase Gene  Pdgfrb
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  true Is Wild Type  false
molecularNote  The targeting cassette consisting of a SA.lox.PDGFRb.lox-Flpo-attB-Neo-attP cassette replaced the exons 2-4 of the endogenous Pdgfrb gene. The PDGFRb is a mouse Pdgfrb gene cDNA. PhiC31 integrase removed the attB-Neo-attP cassette. Cre-mediated recombination removed lox.PDGFRb.lox cassette from Pdgfrbtm1.1(flpo)Leol to enable the expression of the flpo recombinase. This is a nock-in-nock-out null allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Pdgfrb<detalFlp>,
  • bR<deltaFlp>,
  • Pdgfrb<detalFlp>,
  • bR<deltaFlp>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

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Trail: Allele




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