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Allele : Obscn<tm1.1Geno> obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF; targeted mutation 1.1, Genoway

Primary Identifier  MGI:6757165 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence Gene  Obscn
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  An arginine to glutamine substitution at residue 4344 (R4344Q) was introduced in exon 60. An FRT-flanked neomycin selection cassette and loxP site were inserted in intron 59 along with a second loxP site in intron 61 so that the mutant exon 60 and exon 61 are floxed. The selection cassette was removed via Flp-mediated recombination.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • obscurin<R4344Q>,
  • obscurin<R4344Q>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele