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Allele : Anks6<tm1c(KOMP)Wtsi> ankyrin repeat and sterile alpha motif domain containing 6; targeted mutation 1c, Wellcome Trust Sanger Institute

Primary Identifier  MGI:6727367 Allele Type  Targeted
Attribute String  Conditional ready Gene  Anks6
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
description  Mutant cell line EPD0109_5_E04 was used to create mutant mice which demonstrated germline transmission (J:307271).
molecularNote  The L1L2_Bact_P cassette was inserted at position 47050034 of Chromosome 4 upstream of the critical exon 2 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon 2 at position 47050034. The critical exon 2 is thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele.
  • mutations:
  • Insertion
  • synonyms:
  • Anks6<tm1b>,
  • Anks6<tm1b>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories

Trail: Allele