| Primary Identifier | MGI:6783454 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Dyrk1a |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted into intron 7 and an FRT site flanked neomycin resistance gene cassette and second loxP site were inserted into intron 7. The neo cassette was removed through subsequent Flp-mediated recombination, leaving exon 7 floxed. Mutations in the human ortholog are associated with autosomal dominant mental retardation 7 (MRD7). |
