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Allele : Hic1<tm1.1Tmun> hypermethylated in cancer 1; targeted mutation 1.1, T Michael Underhill

Primary Identifier  MGI:6740446 Allele Type  Targeted
Attribute String  Conditional ready, Reporter Gene  Hic1
Transmission  Germline Strain of Origin  129Sv/Pas
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector contained LoxP sites flanking the major coding exon 2 of Hic1, a PGK-neo cassette flanked by FRT sites distal to exon 2 and upstream of the 3' LoxP site. An IRES-NLS-LacZ cassette distal to the 3' LoxP site (downstream of exon 2) was added to enable the efficient identification of Hic1 deleted cells. The male chimeras were bred with female Flippase-expressing mice for deletion of the PGK-neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Hic1<f>,
  • Hic1<f>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele