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Allele : Oga<tm1.1Arte> O-GlcNAcase; targeted mutation 1.1, TaconicArtemis

Primary Identifier  MGI:6783450 Allele Type  Targeted
Attribute String  Not Specified Gene  Oga
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  A mutation was engineered in exon 7 to change aspartic acid codon 285 (GAT) to an alanine codon (GCC)(p.D285A) and an FTR site flanked puromycin resistance gene cassette was inserted into intron 6. The puro cassette was removed through subsequent flp-mediated recombination. The mutation abolishes the O-GlcNAc-related enzymatic activity of the encoded peptide.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • OGA<D285A>,
  • Mgea5<tm3592(D285A)Arte>,
  • OGA<D285A>,
  • Mgea5<tm3592(D285A)Arte>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele