Primary Identifier | MGI:6729236 | Allele Type | Targeted |
Attribute String | Conditional ready, Reporter | Gene | Mecom |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An M2rtTA/IRES, loxP flanked GFP, polyA, and an FRT-flanked neomycin cassette were introduced immediately after the ATG codon in exon 1 of the mouse Mecom gene via homologous recombination in embryonic stem (ES) cells. The resultant mice were crossed with Flp-expressing mice to remove the selection cassette. |