Primary Identifier | MGI:6720293 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Hecw2 |
Transmission | Germline | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct inserted a loxP site upstream of exon 7, a floxed neomycin resistance cassette with a 5â FRT site, IRES, lacZ reporter gene, and FRT were inserted downstream of exon 5. Cre-mediated recombination removed exon 5 through 7 and replaced them with an IRES and lacZ reporter gene. |